Effects on Gene Transcription Profile and Fatty Acid Composition by Genetic Modification of Mevalonate Diphosphate Decarboxylase MVD/Erg19 in Aspergillus Oryzae
Mevalonate diphosphate decarboxylase MVD/Erg19 is required for ergosterol biosynthesis, growth, sporulation, and stress tolerance in Aspergillus oryzae.In this study, Mug RNA-seq was used to analyze the gene transcription profile in AoErg19 overexpression (OE) and RNAi strains.There were 256 and 74 differentially expressed genes (DEGs) in AoErg19 O